Needleless Profhilo

Needleless Profhilo


Rejuvenate and Rehydrate Your Skin.


Based on the proven success of award winning Profhilo injections, Illumia has developed a needleless version using FDA-approved SkinElectroporation® (S.E.P.) technology that is non-invasive, needle-free and painless.

What is Profhilo?

Profhilo is not a dermal filler and does not add volume nor alter the face shape. Instead, it nourishes skin cells by providing hydration from the inside out. The results include healthier skin and a more youthful appearance.Profhilo-HA

Profhilo is a Hybrid Complex made of H-HA and L-HA. This combination of hyaluronic acid’s different molecular weights gives a synergistic effect that benefits the skin. The high molecular weight HA protects the skin’s integrity and ability to retain moisture while the low molecular weight HA hydrates the skin with is hydrophilic properties.

It currently has the highest concentration of Hyaluronic Acid (HA) among other skin boosters. Profhilo also stimulates tissue bio-remodelling, and significant improvements in elastin and collagen can be seen.

Before & After Needleless Profhilo

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Profhilo Clinical Studies

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Clinical Studies of SEP Technology

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Biochemical Studies


Key Benefits

  • Protects skin from premature ageing
  • Restores protective barrier of damaged skin
  • Improves skin firmness and quality
  • Increases elastin and collagen
  • Soothes sensitive, irritated and reddened skin

The latest Needleless Profhilo treatment


For those who are squeamish about needles, the Needleless Profhilo is now available at ILLUMIA, using the FDA-approved World’s 1st Technology to administer the macromolecules into the skin dermis - completely needle-free.

SkinElectroporation™ (S.E.P.) technology is FDA-approved as an alternative drug delivery system to injections, and is clinically-proven to transdermally deliver macromolecules (1 to 2 million dalton) into the skin.

This revolutionary method allows patients with a fear of needles to obtain similar results in an effective needleless way.

How does Needleless Profhilo work?

Profhilo injectables are recommended to be injected strategically into the 3 key layers of the skin at 5 focal points on the face, known as the Bio Aesthetic Points (BAP). There 5 points are also located away from nerves and major blood vessels, which means less risk of injury.

At Illumia, Profhilo is delivered deep into the dermis layer using groundbreaking S.E.P. technology, which is clinically proven to improve molecule absorption up to 17X more than topical application. This allows for the unique composition in Profhilo to penetrate the superficial layers of the skin without the need for any invasive needles.

Clients report feeling no pain and tiny pokes on the skin from the electrical pulses. With this method, there is no downtime, no side effects, and little to no risk of infection.

Profhilo Injections VS Needleless Profhilo

Hand Injection Method Needleless Profhilo Method
Causes skin bumps No skin bumps
Downtime of 2 to 5 days to resolve redness, swelling and bumpiness Zero downtime
Reaches deep dermis layer Reaches deep into the subcutaneous dermis layer
80 - 95% product efficiency 75 - 80% product efficiency

Is Needleless Profhilo effective?

The S.E.P. technology is clinically proven to be effective in delivering substances of various macromolecular weights of up to 2 million dalton* into the dermis layer of the skin while leaving the skin intact. While intradermal injections have slightly less wastage (15% to 20% difference) compared to Needleless Profhilo, many patients cannot afford its lengthy downtime.

Additionally, procedures involving multiple injections have been reported to be one of the most painful aesthetic procedures, while the needleless version causes no pain or discomfort. In conclusion, even with a reduced efficiency of 15 -20%, Needleless Profhilo is still the better option for significantly visible results.

Who is a suitable candidate?

Profhilo is suitable for all skin types and is an ideal treatment for the face, neck and décolletage. It is especially recommended for those with mild to moderate signs of aging, and also fine lines & wrinkles.

Why choose Illumia?

Illumia uses original Profhilo. Each box is tamper-proof and marked with an authenticity sticker, ensuring that it has been transported via pharmaceutical cold chain logistics to Illumia.

FAQs About Illumia's Needleless Profhilo

Is it really needle-free?

Yes! Illumia is known for our signature Skin Electroporation (SEP) technology, which is FDA-approved. It is an innovative method to replace the need for needle injections so patients can enjoy the benefits without the fear of needles.

When will results be visible?

Results are natural and are visible after the first session, but more apparent after 2 sessions, one month apart. You can expect to see a gradual intense hydration and tightening of the skin 2 weeks after the treatment. Eight weeks following the treatment is when you will see the most improvement.

Who is a suitable candidate?

Profhilo is suitable for all skin types and is an ideal treatment for the face, neck and décolletage. It is especially recommended for those with mild to moderate signs of aging, and also those with fine lines & wrinkles.


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